[PDF] Scandinavian Clinical Practice Guidelines on the diagnosis, management and follow‐up of anaphylaxis during anaesthesia * | Semantic Scholar (2024)

The aims were to assess the adequacy of this letter in ensuring this vital communication, and to quantify the effectiveness of the recommendations on the safety of future anaesthesia.

This manuscript addresses some common medical problems that may impact on the anaesthetic of children presenting for surgery, including upper respiratory tract infections, and allergy and asthma; conditions whose optimal management should invoke daily discussions.

Preoperative planning and avoiding cross-reactivity with drugs commonly used during anaesthesia are the key points to prevent an anaphylaxis.

This short narrative review will discuss the recent NAP6 results in the context of current knowledge, as relevant to the South African anaesthetist.

The clinical signs of anaphylaxis occurring during labor and cesarean delivery are identified, the more common allergens that cause anaphYLaxis during this clinical setting are discussed, and a rational approach to the identification of the offending allergen is developed.

...

...

These guidelines represent a consensus of experts in the field of immediate hypersensitivity reactions occurring during anaesthesia and are presented to provide the most valid, widely accepted, effective and easily teachable guidelines.

The methodology, diagnostic algorithm and preliminary results from the Anaesthesiology and Dermatology centre investigating anaphylactoid reactions in anaesthesia are presented.

Since no specific treatment has been shown reliably to prevent the occurrence of anaphylaxis, allergy assessment must be performed in all high-risk patients and the need for proper epidemiological studies and the relative complexity of allergy investigation should be underscored.

The ’’Anaphylactic package’‘, comprising what is needed to perform a proper follow-up of patients with allergic reactions during anaesthesia is introduced, to make it simple for the referral anaesthesiologist.

Immuno-allergic tests enabled one to make the diagnosis of true anaphylaxis in eight cases and of non specific histamine-liberation in five cases; in the other cases, it was impossible to express an opinion.

Neuromuscular blocking agents were the dominating antigens causing immunoglobulin E–mediated anaphylaxis in this study and should be pursued by network formation to produce data more suitable for epidemiologic research.

The incidence of anaesthetic anaphylaxis can be reduced by avoiding latex exposure in patients with spina bifida or latex allergy, and preventing second reactions in Patients with a history of anaphYLaxis, or major undiagnosed or undocumented adverse events during anaesthesia.

With adequate investigation, explanation, and communication, subsequent anaesthesia is safe in this group of patients and the addition of sequential complement measurements in the 24 h post reaction increased reliability of diagnosis.

...

...